Improved glycemic control via a predominantly pharmaceutical approach has demonstrated paradoxical increased cardiovascular risk [ 28 ]. For CCI participants, acid—base physiology was normal; no cases of metabolic acidosis were observed. In type 2 diabetes, which accounts for at least 90 percent of all diabetes cases, beta cells in the pancreas produce some but not enough insulin, or the body cannot process insulin. Lancet Diabetes Endocrinol. None of the adverse events were attributed to the intervention. In-clinic weight for all participants was measured to the nearest 0. Diabetes Ther.
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